Which drug is known to treat glaucoma by decreasing aqueous humor production?

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Timolol Maleate is a non-selective beta-adrenergic antagonist that works primarily by decreasing the production of aqueous humor in the eye. This reduction in aqueous humor is essential for lowering intraocular pressure, which is a critical factor in managing glaucoma. By acting directly on the ciliary body, Timolol reduces the secretion of fluid, thereby decreasing pressure in the eye.

In contrast, other options like Brimonidine and Prostaglandin Analog primarily focus on other mechanisms. Brimonidine, for instance, not only reduces aqueous humor production but also enhances uveoscleral outflow, while Prostaglandin Analog works by increasing the outflow of aqueous humor rather than decreasing its production. Acetazolamide, on the other hand, is a systemic medication that also decreases aqueous humor production but is not the first-line treatment for glaucoma when compared to Timolol. Therefore, Timolol Maleate stands out for its specific action of reducing aqueous humor production, making it a common choice for glaucoma treatment.

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